Hirudin | anticoagulant

Hirudin Extracts by Baoji Hancuikang Bio-Technology Co., Ltd

Our hirudin medicine offer a myriad of health benefits, making them an ideal choice for various applications. Hirudin, the key component, exhibits anticoagulant properties, preventing blood clot formation. Additionally, it has anti-inflammatory effects, promoting overall cardiovascular health.With our advanced extraction process, we ensure the preservation of hirudin's bioactive properties, making our extracts suitable for pharmaceutical, nutraceutical, and cosmetic applications.

Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also known as “Shuizhi” in traditional Chinese medicine), is the strongest natural specific inhibitor of thrombin found so far. Hirudin has been demonstrated to possess potent anti-thrombotic effect in previous studies. Recently, increasing researches have focused on the anti-thrombotic activity of the derivatives of hirudin, mainly because these derivatives have stronger antithrombotic activity and lower bleeding risk. Additionally, various bioactivities of hirudin have been reported as well, including wound repair effect, anti-fibrosis effect, effect on diabetic complications, anti-tumor effect, anti-hyperuricemia effect, effect on cerebral hemorrhage, and others.

In recent years, numerous studies of hirudin and its derivatives have rapidly risen, especially on effects of wound repair, anti-fibrosis, and anti-diabetic complications effects. In addition, the studies of other pharmacological effects including anti-thrombotic effect, anti-tumor effect, anti-hyperuricemia effect, and effects on cerebral hemorrhage, IgA nephropathy, acute lung injury, as well as myocardial infraction have also made some progress.

Specifications

Product name:Leech extract

Other name:Hirudin freeze dried powder

Appearance:Brown to gray powder

Assay:800ATU/g

Latin name:Whitmania pigra Whitman

Use part:Body

Technology:Dry leech-crushing-extract-concentration-spray drying-test-storage

Leech nutrition

The main component of leech is protein, polypeptide, trace element and fatty acid element.

1. Protein: the content of amino acids in leech powder is as high as 62 percent . Among the 17 amino acids, the content of glutamic acid, aspartic acid, lysine and leucine are higher, which can be used as dietary supplements in health products.

2. Polypeptides: Leeches that suck blood contain low molecular polypeptides composed of multiple amino acids.

3. Trace elements: There are eight elements including calcium, chromium, copper, iron, magnesium, manganese, vanadium and zinc, among which vanadium, manganese, copper, iron and zinc are essential trace elements in human body. Zinc is widely involved in the metabolism of protein enzymes, sugars, nucleic acids and fats, etc. Zinc can improve human immunity and has anti-cancer function.

4. Fatty acids: there are 16 fatty acids in the leech, among which 63.34 percent are saturated fatty acids and 34.05 percent are unsaturated fatty acids. It has the functions of regulating human lipid metabolism, treating and preventing cardiovascular and cerebrovascular diseases.

Function and Application

Function

• Hirudin has anticoagulant and antithrombotic effects. Hirudin and hirudin are used in antithrombotic treatment, with small bleeding side effects and no allergic reactions and immunogenicity non-toxic reactions.

• Leech powder can reduce the influence of cerebral ischemia on cerebral nerve function and is an effective drug for treating cerebral ischemia in Traditional Chinese medicine.

• Leech extract can inhibit the formation of tumor blood vessels, leech powder can reduce blood viscosity, promote the blood circulation, make the blood vessels in the organization to get more oxygen and nutrients, improve tumor cell hypoxia state, but also can reduce the expression levels of patients anoxia induced factor, prevent the activation of vascular endothelial growth factor, inhibit the formation of tumor blood vessels, Thus play an anti-tumor role.

• Leeches can cure blood stasis by breaking blood and promote blood circulation.

Application Areas

• Recombinant hirudin polypeptide antithrombotic drugs for the treatment of thrombotic diseases, heparin is commonly used as an anticoagulant drug in the world. Studies have shown that hirudin is superior to heparin in many properties. It has small dosage, does not cause bleeding, and does not depend on endogenous cofactors.

• The natural hirudin produced by our company has more biological activity than synthetic and recombinant hirudin.

• Hirudin powder can be used in the treatment of various thrombotic diseases, especially in the treatment of venous thrombosis and diffuse coagulation.

• It can also be used to prevent the formation of arterial thrombosis after surgery, prevent the formation of thrombus after thrombus dissolution or blood vessel reconstruction;

• Improve external blood circulation and hemodialysis processes; Hirudin can promote wound healing. It prevents metastasis of tumor cells and has been shown to be effective in tumors such as fibrosarcoma, osteosarcoma, hemangiosarcoma, melanoma and leukemia.

• Hirudin can also be used in conjunction with chemotherapy and radiation therapy to enhance efficacy by promoting blood flow in tumors.

• Hirudin is relatively stable, trypsin and chymotrypsin do not destroy its activity, and some hydrolyzed fragments of hirudin can still inhibit thrombin, which can explain why the oral administration of traditional Chinese medicine hirudin extract is still effective.

  
  

Hirudin separates, got from the spit of restorative bloodsuckers, and has without a doubt exhibited an expansive range of utilizations, especially in the fields of drugs, nutraceuticals, and beauty care products. We should dive further into every one of these areas:

1. Pharmaceuticals:

• Cardiovascular Wellbeing: Hirudin is famous for its anticoagulant properties. It restrains thrombin, a pivotal compound in the blood-thickening cycle. This makes it significant in the plan of drugs pointed toward forestalling and treating cardiovascular circumstances. Prescriptions consolidating hirudin might be endorsed to patients in danger of apoplexy, embolism, or other cardiovascular occasions.

• Apoplexy Avoidance: Hirudin's capacity to forestall blood cluster arrangement is especially gainful in circumstances like post-careful recuperation or for patients with specific cardiovascular circumstances. Drug definitions containing hirudin can be customized to explicit patient requirements.

2. Nutraceuticals:

• Blood Course Backing: Hirudin concentrates can be used in nutraceutical supplements intended to help solid blood flow. These enhancements might be suggested for people with conditions like unfortunate dissemination, varicose veins, or those hoping to improve generally speaking cardiovascular prosperity.

• Venous Wellbeing: Given its anticoagulant and vasodilatory impacts, hirudin can be integrated into nutraceutical items pointed toward keeping up with venous well-being. This is especially important for people who might encounter venous deficiency or related issues.

3. Cosmetics:

• Hostile to Maturing Items: Hirudin's capacity to further develop the bloodstream and forestall coagulation can be advantageous in the enemy of maturing beauty care products. Further developed blood flow can upgrade the conveyance of oxygen and supplements to skin cells, advancing a better composition and possibly diminishing the presence of scarcely discernible differences and kinks.

• Skincare Items: The anticoagulant and calming properties of hirudin make it appropriate for skincare definitions. It could be remembered for items intended to alleviate and quiet the skin, making it possibly viable in tending to conditions like redness and disturbance.

• Collagen Creation: By advancing better blood dissemination, hirudin may by implication add to collagen creation in the skin. Collagen is fundamental for keeping up with skin versatility and immovability, making hirudin a significant fixing in surface-level items expected to help skin structure.

In outline, hirudin removes have different applications across drugs, nutraceuticals, and beauty care products, on account of their extraordinary properties. Whether it's forestalling blood clusters in cardiovascular prescriptions, supporting blood flow in nutraceutical supplements, or improving skin well-being in beauty care products, hirudin keeps on being a flexible fixing in different businesses.

OEM Services

We take pride in offering OEM services to meet your specific requirements. Collaborate with us to create custom formulations, packaging, and branding, tailored to your market needs. Our experienced team ensures a seamless OEM experience with a focus on quality and innovation.

Package

Our advantage 

As a supplier of Hirudin extract for 15 years, we can guarantee the quality of products, we can provide different customized services.If you have any requirements, please contact us.

1. Timely online communication and reply within 12 hours;

2. Choose high-quality raw materials;

3. OEM/ODM available;

4. Reasonable and competitive price;

5. Free samples can be provided;

6.  Fast delivery time: stable inventory of products;Mass production within 7 days;

We are the manufacturer of the Hirudin powder, satisfying the standard of ISO9001, we undertake OEM business. 

FAQ

※ Do you have factory ?

Yes, sure, we have factory, welcome to visit our factory. When you have the details schedule, please kindly let me know in advance.

※ What is your delivery time ?

We have enough stocks, after receipt your confirmation, we will arrange for you within 2~3 days.

※ How can you confirm your quality?

Each batch of the goods can be shipped to you after strict inspection, if you still doubt, we can arrange the Pre-shipment Samples to your testing or to your pointed third party for retesting, successfully, then we will arrange the bulk goods to you immediately.

In conclusion, Baoji Hancuikang Bio-Technology Co., Ltd is your trusted partner for premium natural hirudin. Our facility, extensive inventory, and commitment to quality make us a preferred choice. Contact us today for a reliable supply of top-notch Hirudin Extracts, crafted to elevate your formulations.

Contact Us

With the concept of “Quality First, Integrity First”,  Hancuikang Bio-Technology Co., Ltd. are strictly performing the standard in production and quality control of Nutmeg Extract Powder. Independent laboratory and famous third party retest confirm that each batch is qualified.If you have any questions, please contact us freely. Email: fxu45118@gmail.com or WhatsApp/ Wechat:13379475662

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