Berberine Hydrochloride is an important alkaloid, is the application of traditional Chinese medicine for a long time. It can be extracted from berberine, Cork, three needles and other plants. It has a significant inhibitory effect.Berberine Hydrochloride can fight pathogenic microorganisms, for a variety of bacteria such as dysentery bacillus, Mycobacterium tuberculosis, pneumococcal, diphtheria and typhoid bacilli are inhibited, in which the role of Shigella most commonly used to treat bacterial gastroenteritis, dysentery and other gastrointestinal diseases. Primarily for the treatment of bacterial dysentery and gastroenteritis, it fewer side effects.
Berberine Hydrochloride Powder
Specification
Berberine HCL |
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Grade |
Resource |
Specification |
|
Human Grade |
Fibraurea recisa Pierre |
itrimetric Method |
HPLC Method |
97%(CP2005) | 91%-92% | ||
Phellodendron |
98%(CP2015) |
95%-97% | |
Veterinary Grade |
Fibraurea recisa Pierre |
90% |
30% |
Berberine Sulfate |
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Resource |
Specification |
|
Phellodendron |
Titrimetric Method |
HPLC Method |
98% |
95% |
Certificate of Analysis
Analysis |
Specifications |
Results |
Appearance |
Fine powder |
Complied |
Color |
Yellow Crystal |
Complied |
Odor |
Characteristic |
Complied |
Assay |
≥97% |
97.36% |
Identification |
positive |
Positive |
Other alkaloid |
complied |
Complied |
Loss on drying |
≤12% |
11.10% |
Residue on drying |
≤0.2% |
0.16% |
Total Plate |
<1000CFU/g |
Complied |
Yeast&mold |
<100CFU/g |
Complied |
Salmonella |
Negative |
Negative |
E.Coli |
Negative |
Negative |
Test standard |
Ch.P-2010 |
Ch.P-2010 |
Function
1. Regulates blood sugar: Berberine hydrochloride has been shown to improve blood glucose levels in people with type 2 diabetes. One study found that berberine hydrochloride worked as well as metformin, a commonly prescribed diabetes drug.
2. Lowers cholesterol: Berberine hydrochloride has been shown to lower blood cholesterol levels, particularly the "bad" LDL cholesterol. This may help reduce the risk of heart disease.
3. Anti-inflammatory: Berberine hydrochloride has potent anti-inflammatory effects, which may help reduce inflammation in the body and alleviate related health issues.
4. Anti-tumor: Berberine hydrochloride has been found to inhibit the growth of various types of cancer cells, including breast, liver, and lung cancer cells.
5. Antibacterial: Berberine hydrochloride has antimicrobial properties, which may help fight bacterial infections and support immune system function.
The production process of berberine hydrochloride:
1.Extraction: The first step in the process is to extract berberine from a plant source, usually Coptis chinensis or Berberis spp. The dried roots or bark of the plant are usually used for extraction. Plant material is finely ground and mixed with a suitable solvent such as ethanol or water, then heated or macerated. This facilitates the extraction of berberine alkaloids from plant material.
2. Filtration: After extraction, the mixture is filtered to separate the liquid extract from any solid plant material. This can be done using various filtration techniques such as filtering through filter paper or using a filter membrane.
3. Concentration: The filtered extract is then concentrated to increase the berberine concentration. This can be achieved by various methods such as evaporation, vacuum distillation or freeze drying. This step helps to obtain a higher yield of berberine.
4. Precipitation: The concentrated extract is precipitated by adding suitable reagents. For berberine hydrochloride, hydrochloric acid (HCl) is generally used. The addition of HCl helps to convert berberine into more stable and soluble berberine hydrochloride.
5. Filtration and washing: The berberine hydrochloride precipitate is then filtered to separate it from the liquid. Wash it with a suitable solvent, such as ethanol or water, to remove any impurities or residual reagents.
Drying: The washed berberine hydrochloride is then dried to remove any residual solvent or moisture.
Packaging
Ship and Delivery
Transit could be DHL,UPS,TNT, FEDEX, EMS. For mass orders, it will be delivered by air or sea.
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