berberine hcl bulk

Specification:Berberine HCL 97%/98% HPLC
Appearance: yellow fine powder
Solubility: Soluble in water, insoluble in benzene, ether and chloroform
Package: 1kg/foil bag, or 20kg/drum

Berberine Hydrochloride is an important alkaloid, is the application of traditional Chinese medicine for a long time. It can be extracted from berberine, Cork, three needles and other plants. It has a significant inhibitory effect.Berberine Hydrochloride can fight pathogenic microorganisms, for a variety of bacteria such as dysentery bacillus, Mycobacterium tuberculosis, pneumococcal, diphtheria and typhoid bacilli are inhibited, in which the role of Shigella most commonly used to treat bacterial gastroenteritis, dysentery and other gastrointestinal diseases. Primarily for the treatment of bacterial dysentery and gastroenteritis, it fewer side effects.

Berberine Hydrochloride

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Berberine Hydrochloride Powder

Specification

Berberine HCL

Grade

Resource

Specification

Human Grade

Fibraurea recisa Pierre

itrimetric Method

HPLC Method

97%(CP2005) 91%-92%

Phellodendron

98%(CP2015)

95%-97%

Veterinary Grade

Fibraurea recisa Pierre

90%

30%

Berberine Sulfate

Resource

Specification

Phellodendron

Titrimetric Method

HPLC Method

98%

95%

Certificate of Analysis

Analysis

Specifications

Results

Appearance

Fine powder

Complied

Color

Yellow Crystal

Complied

Odor

Characteristic

Complied

Assay

≥97%

97.36%

Identification

positive

Positive

Other alkaloid

complied

Complied

Loss on drying

≤12%

11.10%

Residue on drying

≤0.2%

0.16%

Total Plate

<1000CFU/g

Complied

Yeast&mold

<100CFU/g

Complied

Salmonella

Negative

Negative

E.Coli

Negative

Negative

Test standard

Ch.P-2010

Ch.P-2010

Function

1. Regulates blood sugar: Berberine hydrochloride has been shown to improve blood glucose levels in people with type 2 diabetes. One study found that berberine hydrochloride worked as well as metformin, a commonly prescribed diabetes drug.

2. Lowers cholesterol: Berberine hydrochloride has been shown to lower blood cholesterol levels, particularly the "bad" LDL cholesterol. This may help reduce the risk of heart disease.

3. Anti-inflammatory: Berberine hydrochloride has potent anti-inflammatory effects, which may help reduce inflammation in the body and alleviate related health issues.

4. Anti-tumor: Berberine hydrochloride has been found to inhibit the growth of various types of cancer cells, including breast, liver, and lung cancer cells.

5. Antibacterial: Berberine hydrochloride has antimicrobial properties, which may help fight bacterial infections and support immune system function.

The production process of berberine hydrochloride:

1.Extraction: The first step in the process is to extract berberine from a plant source, usually Coptis chinensis or Berberis spp. The dried roots or bark of the plant are usually used for extraction. Plant material is finely ground and mixed with a suitable solvent such as ethanol or water, then heated or macerated. This facilitates the extraction of berberine alkaloids from plant material.

2. Filtration: After extraction, the mixture is filtered to separate the liquid extract from any solid plant material. This can be done using various filtration techniques such as filtering through filter paper or using a filter membrane.

3. Concentration: The filtered extract is then concentrated to increase the berberine concentration. This can be achieved by various methods such as evaporation, vacuum distillation or freeze drying. This step helps to obtain a higher yield of berberine.

4. Precipitation: The concentrated extract is precipitated by adding suitable reagents. For berberine hydrochloride, hydrochloric acid (HCl) is generally used. The addition of HCl helps to convert berberine into more stable and soluble berberine hydrochloride.

5. Filtration and washing: The berberine hydrochloride precipitate is then filtered to separate it from the liquid. Wash it with a suitable solvent, such as ethanol or water, to remove any impurities or residual reagents.

Drying: The washed berberine hydrochloride is then dried to remove any residual solvent or moisture.

Packaging

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Ship and Delivery

Transit could be DHL,UPS,TNT, FEDEX, EMS. For mass orders, it will be delivered by air or sea.

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The company always adheres to the corporate mission of creating healthy life, strictly controls product quality and is certified with ISO9001 quality management system certificate, BRC,IFS,FDA,Halal and Kosher certificates. The company is continuously making innovations and developments and has being issued with high-tech enterprise certificate for many consecutive years. At the same time, it was granted a number of patent for inventions by State Intellectual property Office(SIPO).

Our Factory

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