Black Pepper Extract Piperine

Black Pepper Extract Piperine: The Must-Have Ingredient for Health and Wellness Products

As a manufacturer located in China, we are proud to offer one of our most innovative and researched products, black pepper extract piperine. This product is a game-changer for the health and wellness industry, and we are excited to share its benefits with merchants outside of China.

Black pepper extract (Piper nigrum) is a natural herb that has been used for centuries in traditional medicine. Piperine is the active compound found in black pepper that gives it its pungent and spicy flavor. Piperine has also been found to have numerous health benefits, including enhancing the bioavailability of other nutrients, aiding digestion, and reducing inflammation.

Our product, black pepper extract piperine, is a highly concentrated extract of piperine. It is a 100% natural and safe product, free from any synthetic compounds or additives. The extraction process is also eco-friendly, ensuring that the purity and potency of the product are not compromised.

product details

Product Name:  High quality 98% bioperine black pepper extract

Active ingredients:  Piperine

Spec./Purity:  98%

Part Used:  Seed

COA

Black Pepper Extract Piperine Benefits:

1.Increasing Supplement/Drug Bioavailability

Black pepper extract piperine was identified in 1979 as the first-ever compound ever that enhances the “bioavailability” of other substances. In other words, piperine increases the ability of the body to use nutrients and drugs.This means that lower or fewer doses of the drug can be used to achieve the same effect. This is very beneficial when it comes to drugs that have unpleasant side effects!

1)Piperine black pepper extract may protect against oxidative stress by removing free radicals (such as hydroxyl and superoxide) from the body.In a small trial on 20 people with pancreatitis, a combination of curcumin (500 mg) and piperine (5 mg) improved their status (lower fat peroxidation and MDA and higher glutathione levels). Combinations with the same proportion of curcumin and piperine also improved status in 3 trials on over 100 people with metabolic syndrome, almost 100 people with chronic lung disease, and 40 people with osteoarthritis.

2) Inflammation

In a clinical trial on over 100 people with type 2 diabetes or metabolic syndrome, a combination of curcumin and piperine had effects (measured as lower CRP levels). However, the mix contained 100x more curcumin than piperine. A similar mix also reduced inflammation (reduced levels of IL4, IL-6, and CRP) in a clinical trial on 40 people with knee osteoarthritis. Piperine reduced both short- and long-term symptoms of inflammation in rats.

3) Improving Blood Cholesterol

In 2 clinical trials on over 200 people with type 2 diabetes or metabolic syndrome, a combination of 1,000 mg/day curcumin and 10 mg/day piperine lowered total cholesterol and LDL- and VLDL cholesterol (the “bad”type) while increasing HDL-cholesterol (the “good” type).

4) Metabolic Syndrome

As previously mentioned, the combination of curcumin (1,000 mg/day) and black pepper extract piperine (10 mg/day) improved oxidative, inflammatory, and blood fat status in 2 clinical trials on over 200 people.

5) Lowering Blood Sugar

In a clinical trial on 100 people with type 2 diabetes, a combination of 500 mg/day curcumin and 5 mg/day piperine lowered blood sugar and reduced liver damage. In diabetic mice, a low dose of piperine (20 mg/kg body weight) reduced blood sugar. However, higher doses increased blood sugar levels.

6) Vitiligo

Vitiligo is a long-term condition in which skin patches lose pigmentation. In a clinical trial on 63 people with vitiligo on the face, a combined therapy of piperine and narrowband UV-B radiation enhanced skin repigmentation [39].

Animal and Cell Research (Lack of Evidence)

No clinical evidence supports the use of piperine for any of the conditions listed in this section. Below is a summary of the existing animal and cell-based research, which should guide further investigational efforts. However, the studies should not be interpreted as supportive of any health benefit.

7.Cognitive Function

Multiple animal studies suggest that piperine can boost brain function .

8.Depression

Piperine black pepper extract had effects in mice subjected to chronic stress. This effect was linked to the increased production of new brain cells and increased BDNF levels in the hippocampus. Depression is common in epilepsy. In rats with epilepsy, dietary piperine reduced symptoms of depression by increasing serotonin levels.

9.Parkinson’s Disease

In mice with Parkinson’s disease, piperine improved motor coordination. It also improved brain function and learning. Increasing dopamine levels is the most common way to treat Parkinson’s disease. Piperine inhibits MAO-A and MAO-B, the enzymes that break down dopamine, possibly increasing overall dopamine levels in the brain. Piperine also prevented the death of dopamine neurons in mice. It protected neurons because it is an , is , and prevents programmed cell death.

10.Allergies

Piperine reduces inflammation and suppresses the immune system, making it a good candidate for treating and preventing allergies. In mice, piperine reduces sneezing, nose-rubbing, and other symptoms of allergies. It dose-dependently decreased histamine, nitric oxide, IgE, and inflammatory cytokines IL-6 and IL-1b.

11.Pain

As little as 5 milligrams of piperine per kilogram of body weight reduced pain in mice and rats. In humans, this would be roughly equivalent to 1/6th of a teaspoon. Another study in mice showed that higher doses, around 30 to 70 mg per kg body weight, had a similar effect to indomethacin, a pain-relieving drug similar to aspirin or ibuprofen.

12.Weight Loss

Rats with high levels of fats and cholesterol in the blood lost weight and fat mass when piperine was added to their diet.

13.Lowering Blood Pressure

Piperine caused a significant drop in average blood pressure when fed to rats. In another study in rats, it was able to partially prevent the increase in blood pressure caused by a drug (NOS inhibitor).

14. Preventing Gallstones

Gallstones are formed from crystallized cholesterol in the gallbladder. Piperine prevented cholesterol gallstone formation in mice by reducing the size of cholesterol crystals and decreasing the transport of cholesterol from the liver into the gallbladder.

15. Diarrhea

Piperine prevented diarrhea in mice. In rabbits and guinea pigs, it worked as well as loperamide, another drug used to treat diarrhea – but without causing any of loperamide’s usual side effects.

16. Ulcers

Piperine prevented the formation of ulcers in rats and mice. It was effective against ulcers caused by stress, hydrochloric acid, and the pain reliever indomethacin.

Heliobacter pylori is a bacteria that causes chronic stomach inflammation, peptic ulcers, and, in rare cases, stomach cancer. Piperine inhibited H. pylori from growing and sticking to cells, which may reduce the chances of infection.

17. Seizures

In many (but not all) rodent models of epilepsy, piperine reduced the number of seizures and deaths from seizures with doses as low as 10 mg per kg of body weight.

18. Cancer

In skin cancer (melanoma), piperine prevented tumor cells from spreading to other parts of the body (metastasis) leading to significantly better survival rates in mice.

It also decreased tumor growth and metastasis in mice with breast cancer.

Product Function and Application

1. It has the function of treatment for arthritis, rheumatism and skin disease or wound healing;

2. It has the function of losing weight, its ability to increase in the metabolic rate of the body;

3. It has the function of clearing heat and diuretic, expectorant, sedative and analgestic;

4. It has the function of treating acute conjunctivitis, bronchitis, gastritis, enteritis and urinary stones;

5. It has the function of enhancing immunity and supporting the intestinal absorption of nutrients.

Main Function

1. Nutrient absorption

This effect is called "bio-enhancement". Piperine has been shown to increase the absorption of vitamin C, selenium, beta-carotene, vitamin A, vitamin B6 and coenzyme Q10.

2. Immunomodulators

Piperine may reduce the communication of lymphocytes in the immune system, thereby slowing their activity, and piperine has also been shown to be beneficial for gout.

3. Anti-tumor effect

Research suggests that piperine may have certain cancer-fighting properties.

4. Antidepressants

Piperine may also have some antidepressant activity. Animal studies have shown that this supplement has antidepressant and cognitive enhancing effects. Another study found that piperine increased the transmission of the neurotransmitters serotonin and dopamine, two chemicals that are often deficient in people with depression.

Shipping and Serving

1.Packing: Net Weight:25kg/Drum, Gross Weight:28kg/Drum.

2.Shipment: We could arrange the goods by EMS, Fedex, DHL,TNT or by sea. Please contact us if u have further requirements.

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One of the main benefits of black pepper extract piperine is its ability to enhance the bioavailability of other nutrients. Bioavailability refers to the degree to which a substance is absorbed and utilized by the body. Many nutrients are not easily absorbed by the body and may be excreted before they can be fully utilized.

Black pepper extract piperine has been shown to increase the bioavailability of several nutrients, including curcumin (found in turmeric), resveratrol (found in red wine), and EGCG (found in green tea). This means that products containing black pepper extract piperine can be more effective in delivering these nutrients to the body.

Another benefit of black pepper extract piperine is its ability to aid digestion. Piperine has been shown to increase the secretion of digestive enzymes, which can help improve the absorption of nutrients in the gut. It also helps to reduce inflammation in the gut, which can improve overall digestive health.

Inflammation is a key driver of many chronic diseases, including heart disease, diabetes, and cancer. Black pepper extract piperine has anti-inflammatory properties, which can help reduce the risk of these diseases. It has also been shown to have antioxidant properties, which can help protect the body against damage from free radicals.

Overall, black pepper extract piperine is a must-have ingredient for health and wellness products. Its ability to enhance the bioavailability of nutrients, aid digestion, and reduce inflammation makes it a highly sought-after ingredient for supplements, functional foods, and beverages.

Our product, black pepper extract piperine, is available in both powder and liquid form. It is highly concentrated, so only a small amount is needed to achieve the desired effect. It is also easy to incorporate into existing products, as it has a neutral taste and odor.

In conclusion, black pepper extract piperine is a highly innovative and researched product that has numerous health benefits. Its ability to enhance the bioavailability of nutrients, aid digestion, and reduce inflammation makes it a must-have ingredient for any health and wellness product. We are excited to offer this product to merchants outside of China, and we are confident that it will be a valuable addition to their product lines.

What is Black Pepper Extract Piperine?

Black pepper extract piperine is an ingredient extracted from black pepper, pepper root, and long pepper, which gives peppers its spicy flavor. This extract is marketed as a nutritional supplement and has been found to increase the absorption of various nutrients. Studies have found that piperine has immunosuppressive, tumor suppressive and antidepressant effects.

Piperine can indeed improve the bioavailability of various drugs, nutrients and other substances (such as garbanine, duckbilline, quercetin, resveratrol, coenzyme Q10, vitamin B6, etc.). It works by accelerating the rate of absorption of these substances in the gastrointestinal tract, or by protecting the absorbed part from being metabolized and broken down by the liver. Of course, it is also possible. Among them, the best match for piperine is curcumin.

Our main products

Extract of Salicornia fruticosa: Aescinate UV20%, UV40%,

Hplc20%, 98% titration, 98% sodium aescinate;

Extracts of pseudophyllostachys ruxerata: UV5%, UV10%, UV20%.

The extracts of melaleuca: Huperzine a 1%, 5%, 98%;

Sinomenine hydrochloride 98%; 10% water-soluble piperine, 95% piperine;

Artemisinin: 98%; Apigenin 95% 98%;

Evodia rutaecarine 98%; Phosphatidylserine PS 20%-70%;

We are focused on product's Quality and Services in the whole process. Welcome to send an inquiry to fxu45118@gailm.com or wechat 13379475662 at any time if you need Black Pepper Extract Piperine.