Taxus Chinensis Extract Taxol 98%

Product Description

Taxol is a monomer diterpenoid compound extracted from the bark of natural plant Taxus. It is a complex secondary metabolite and the only drug known to promote microtubule polymerization and stabilize polymerized microtubules. Isotope tracers showed that paclitaxel only binds to polymerized microtubules and does not react with unpolymerized tubulin dimers. After contact with paclitaxel, cells will accumulate a large number of microtubules in the cell, and the accumulation of these microtubules interferes with various functions of the cell, especially stops the cell division in the mitosis period and blocks the normal division of the cell. Through Ⅱ-Ⅲ clinical studies, paclitaxel is mainly applicable to ovarian cancer and breast cancer, lung cancer, colorectal cancer, melanoma, head and neck cancer, lymphoma, brain tumor also has a certain effect.

Product Overview

Key Features

We are instrumental in providing to our valuable customers excellent quality Paclitaxel 98% which is available with following specification:-
Active ingredients:Paclitaxel
Appearance:white powder
Purity:98%
Test method:HPLC
Plant source:taxus chinensis
CAS NO.:33069-62-4
MF:C47H51NO14
MW:853.92

Product Character

The appearance is white crystalline or amorphous powder. It was first isolated from Taxus brevifolia by American chemist Wall et al in 1967. It can bind to tubulin and promote the assembly of tubulin into microtubule dimer, thus inhibiting cell microtubule depolymerization and preventing rapid cell reproduction. Clinical trials have shown that paclitaxel has significant efficacy in the treatment of metastatic ovarian cancer and breast cancer, as well as in the treatment of small cell and non-small cell lung cancer, cervical cancer, and anti-chemotherapy leukemia. Taxol only exists in Taxus taxus, of which there are 11 species. There are 4 species and 1 variety in China, which are taxus Yunnan, Taxus Tibet (also known as Himalaya Taxus), Chinese taxus taxus and southern Taxus taxus (also known as beautiful Taxus Taxus). In addition to taxol, these plants also contain a variety of other taxane diterpenoids.

Product Application

Taxol has a good therapeutic effect on ovarian cancer, platinum and other resistant ovarian cancer and breast cancer, and has a good prospect for the treatment of prostate cancer, head and neck cancer, esophageal cancer, germ cell tumor, endometrial cancer, lymphoma, bladder cancer, upper gastrointestinal cancer, small cell and non-small cell lung cancer.

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